Furthermore, MSC transplantation has been considered safe and widely assessed in clinical settings of various diseases with promising results. 7 Additionally, MSCs are safe in terms of ethical concerns because they do not originate from somatic cells. 6 They have self-renewal ability and can differentiate into cells of various lineages, including osteoblasts, adipocytes, and chondrocytes. 4, 5 Of these cell types, MSCs have been shown to have the advantages of being obtained relatively easily and possessing low immunogenicity. Stem cell transplantation including hematopoietic, induced pluripotent, and mesenchymal stem cells (MSCs) can be manipulated for division into hepatocyte-like cells both in vitro and in vivo. Stem cell transplantation has been proposed as a potential strategy for patients with hepatic diseases to prevent progression and treat those with advanced fibrosis. 3 However, transplants are not readily available in many countries, and in countries where transplants are available, organ shortages and high costs related with transplantation make this an impractical option for many patients. 1, 2 The ultimate treatment for end-stage cirrhosis is liver transplantation. It may be necessary to first receive a course of treatment for the viral component.Chronic liver injury, such as that arising from viral infection, alcohol abuse, or metabolic diseases, causes liver cirrhosis and failure. First, you will need to determine at what stage your disease is.
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